Original: Li Sheng
For
Co-founder of Athelas
Deepika Bodapati and Tanay Tandon
Listening carefully is a superpower
One night four years ago
Deepika stays up all night looking through messages received on company's official website
Like Atelas
Family
Founder of a start-up company that is about to become a unicorn in industry
Look at company
Messaging on official website is already part of her daily routine
She smiled and said
Sometimes we also receive messages from employees' parents
I will read all comments
Your feedback is very interesting
And in request and offer messages
She noticed
The lady whose name is constantly mentioned is Dr. Deanna Kelly
She showed great perseverance
Always leave us a message
Deepika remembers
Original
Dr. Kelly from Maryland
Director of Therapeutic Research Program at Center for Psychiatric Research
She keeps posting
I want to know more
Some information about Athelas Athelas One
And tell yourself
May help with further development and testing
At that time
Deepika and Tanai
Difficult to apply for FDA Round 2 for Athelas One
Approval (US Food and Drug Administration)
If anyone can help me, I'd love it
Therefore
Deepika did what she does best
Call Dr. Kelly
Listen to her opinion
This action was repeated countless times
I decided that I should be able to create better products
Grow your business
Actually
Promote transformation of healthcare industry
It's very simple - find people who really need help
And listen to them
——Deepika Bodapati, co-founder of Athelas
I explain listening. Data and Intuition
Listen
This has always been a core competency of Deepika's creative process
It is she who pays attention and listens to data and intuition
There is Atelas One
Unique
Birth of FDA-approved home blood analyzer
Traditional blood test methods
It is necessary to take a drop of patient's blood and stain it on a glass slide
Then put it under microscope
To determine corresponding cell number
And
Athelas One uses computers
Vision and machine learning automate this process
Home User
You can measure your white blood cells and neutrophils
and over Internet
Send test data to appropriate medical facility
Enabling doctors to diagnose remotely
As a researcher
DIpika and Tanay know Athelas One needs more data
Go out to people
Prove that it continues to work accurately and without errors
As entrepreneurs, they also know
Speeding up clinical trials is critical to company's development
But do it once
Clinical trials are not easy
In 2016
Deepika and Tanay in Juarez, Mexico. Juarez
Find a hospital willing to take part in pilot project
and there
First clinical trial of Athelas One completed
Deepika said
Hospital
I immediately saw value of Athelas One for patients
Then hospital set table
Set aside our equipment
Other side
A nurse has been assigned to draw blood and samples
Then
Compare with Athelas One
To ensure accurate results
Deepika
Sit at a table in hallway
Holding Athelas One and a lancet on her fingertip
Glass sample strip
Tanai is sitting in another room
View results on a computer monitor
When hospital tells everyone. Next three days
All
You can come here for a free blood test
Patients come from all directions
Where
When a patient has a scheduled appointment with a doctor
I accidentally took a blood test
No one thought that this would be a turning point in his life
sit down
Tanay in front of computer immediately saw abnormality of result
Normal white blood cell count is usually between 6000 and 8000
And white blood cell count of this patient
much more than 40000
Tanay
Show result to Deepika immediately
They also found that these cells were immature
This
This patient has massive proliferation of leukocytes
This means
This patient probably has leukemia
But since Athelas One
Not yet certified as a medical diagnostic device by FDA
They do not have opportunity to directly inform patient about diagnosis
I can only remind hospital staff
This patient needs to be tested for cancer
Deepika
Remember, I'm going back to California in a few days
She quietly sat next to Tanai
They were both deeply shocked by events of recent days
For first time, she experienced full power of real-time detection
The patients only need to prick their fingers
Wait a few minutes to get result in place
Instead of weekly testing as with traditional testing
Although
They didn't talk much along way
No Deepika
Obviously, I heard my inner voice
The company has more than just a bright future
They can also make world a better place
Creating Bigger Health Change
Tonly on this plane
It suddenly dawned on me
Deepika remembers
We need to make tools cheap enough and easy to use
People can do it anytime, anywhereHelpful
That's it
People can indeed have preventive health protection
Currently Sequoia
We work closely with Athelas
Same as Deepika and Tanai
Sequoia Partner
I also think there should be a faster blood test
A more precise method
When fate knocks at door
Sometimes
The signal that will send Deepika forward
From a message or something similar, but sometimes
There is also influence of fate
Athelas may have today
I can't live without someone
Stanford student and basketball player Michael Morris
First test user of Athelas One
Michael has already been treated for cancer
Therefore
You need to constantly monitor level of leukocytes to prevent a relapse
When he found out
When two of my college classmates were designing hardware
I'm delighted
Found Atelas office in Mountain View
Shabby little bar
Tell them they are ready to experiment. Mouse
Michael's enthusiasm has infected entire office
Tanay said
For a small team of only 4-5 people early on
There are real patients who continue to leave positive reviews
Really very important and useful
Soon
FDA sent another document
demand
Give more information about Athelas One
This is them
Necessary procedures for further analysis of effectiveness of product
Although
Clinical trials in Mexico
Prove that Athelas One works
But FDA felt this wasn't enough and asked for more tests
Although this is standard FDA procedure
But a questionnaire with more than 40 lines is still a little intimidating
In addition, it is necessary to collect experimental data for 8 months
And do more experiments
And this does not guarantee that they will receive FDA clearance
But Deepika said
Inspired by Michael's confidence in product
Let
Aged
Second test completed
After sending various additional materials
They finally got FDA approval
She said
Michael's constant help gave everyone courage
This is his constant feedback
Helped Athelas One get better
Unfortunately
In 2017, Michael left everyone forever
But he really believes in future of Athelas One
Deepika said
He was real first supporter of Athelas One
This is a bright light that leads everyone forward
He told us
'I guess I can't wait
But don't forget to pass it on to others in need
Deepika always remembers his words
Deepika
I develop ability to listen from childhood
Be at home
Still in his uncle's research lab at Stanford
Deepika's parents
Small technology business owner with operations in US and India
Because of time difference
They
Often with foreign teams they send Deepika to school
On phone
Deepika in back seat
You can hear your parents talking on phone
Discuss collaboration
Strategy discussions, business negotiations, etc.
Pros and cons of running a business
It was shown in front of her in a very intuitive way
Deepika's uncle, Dr. Gambhir
He is Department of Radiology at Stanford University
Also a pioneer in development of molecular imaging techniques and early detection of cancer
He loves more than just medical innovation
I also want to really improve lives of cancer patients
Deepika
She worked in her uncle's laboratory for many years
Influenced by my ears
She also had a desire to revolutionize healthcare
Ideas for comprehensively improving people's lives
With Dr. Gambhir
Continued research in early cancer detection technologies
he's slow
Become a leader in development of tools in this field
These tools can collect data in a minimally invasive way
For passive monitoring of patients' health
For example
Checking data related to faeces and urine
Smart toilet to detect early signs of disease
Dr. Gambheer's big dream
Yes
Create a comprehensive preventive medical system with active detection
Not like now
What goes wrong can only be solved individually
Today
Deepika is working hard to make it happen
She said
I am who I am now
Some reasons
He is also influenced by his uncle and his lab
Influence of work experience
Removing "side effects" of clozapine
On other side of America
—Suburbs of Baltimore
Maryland Center for Psychiatric Research
Dr. Dina Kelly, Director and Head of Therapeutic Research Program
Thinking about developing or looking for a nursing device
to help her schizophrenia
Patients are better off using antipsychotic drug clozapine. clozapine
Over past 20 years
Dr. Kelly
Took clozapine
and we believe it will change many forms of treatment-resistant schizophrenia
Patient life
And among those diagnosed with schizophrenia
Up to 30% or more of populationare classified as "resistant" patients
She thinks
With and without this drug
For patients it will be
The difference between indoor home surveillance and independent living
But clozapine
There is biggest side effect
Agranulocytosis may develop after administration
Decrease in white blood cell count
To point of being unable to fight other infections in body
Therefore
Patients should constantly monitor number of leukocytes
When FDA approved use of clozapine
Patients are also asked to have weekly laboratory tests for first 6 months
Shortened to two weeks over next 6 months
Once a month during entire course of treatment
This
Most patients will live their entire lives while on medication
Continue taking blood tests
This is a challenge for everyone
Not to mention people with mental illness
Therefore
Dr. Kelly and her colleagues at University of Maryland at College Park
I experimented with electrochemical detection methods
For monitoring blood levels and neutrophil counts
But no progress
After getting to know Athelas One
I can't even believe such a device exists
Dr. Kelly remembers
Then I kept trying to contact them
I was thinking
If there is such a good device
This will be a very important breakthrough in medicine
This will greatly facilitate patient's condition
It will also revolutionize how we care for patients
So
There is a scene described in introduction to this article
Fortunately
Deepika "heard" her thoughts
So
When Athelas One received its second round of FDA approval
When a patient is considered to be able to use device at home
Dr. Kelly is very excited
This means
With Athelas One at home, patients can simply draw blood with their fingertips
You can do a blood test
Results will be sent to doctors and pharmacists immediately
According to results, pharmacist prescribes medicine and delivers it directly to patient
Dr. Kelly said
Some patients are so poor they can't even afford transportation
Some patients have cognitive impairment
These circumstances determined that they almost
It is impossible to get good treatment through traditional healthcare system
Athelas approach is very clever
Integration of test results in (risk assessment management)
Based on system
Cooperation with remote drug ordering
This makes taking medications and monitoring patients much easier
After
Deepika and her team
We made an effort to get through Athelas One and enter California
Channels of various hospitals
Especially some forensic and county-level medical institutions
They
For a large number of homeless patients with treatment-resistant schizophrenia
Simultaneously
HLS Therapeutics, one of manufacturers of clozapine
Hearing about Deepika and Tanay's work
An invitation to cooperate has also been sent
Help them
Athelas Extended Practice Including Mental Health
Areas other than oncology, such as health
From diagnosing diseases to preventing them
When world
When I started to feel impact of new corona epidemic
Deepika started "listening" again
But this time it's different
She wants Atelas
Transition from stage of participation in diagnosis of diseases to stage of disease prevention
When world is suddenly forced to hit pause button
We
From second application to FDA for clearance
Pass through device
I gained a lot of experience in process of entering a medical institution
Tanay said
We can certainly operate as a traditional biotech company
but
We have a great opportunity
This is a synthesis of experiences we've gained along way
Benefit to a wider audience
Help them during difficult period of epidemic
Simultaneously
We have also moved further in disease prevention
Deepika
A Southern California psychiatrist named Gustavo Alva
When making a commercial call
I found a new opportunity
When Deepika
Asked about needs of those not taking clozapine
Dr. Gustavo said
Most people experience, for example, weight gain
Side effects such as high blood pressure and type 2 diabetes
Keep asking
How these patients monitor their health for a long time
He said
These issues are usually addressed to attending physician
So, Deepika
Feel free to ask Dr. Gustavo
Introduce her to some patients who are willing to chat
To see Athelas One
Could you help me
She found out on phone
Patients usually go to specialists, not general practitioners
Facing these new demands
Deepika and Tanai
Get started building a set of predictive network tools
It is convenient for patients to contact doctors to monitor their health status
Then
They also developed app
Help patients record information and schedule appointments
Our products are slowly evolving in this way
Deepika said
For night
We have increased number of patients from 10 to 600
EvenTanay
A drug use tracker has also been developed
Yes
Works with Athelas One
Helps doctors and patients determine how well their medications are working
Or is it wrong way of perceiving
Therefore
Reduce burden of self-tracking a patient
When Deepika tried to bill for monitoring services provided by Athelas
Health insurance queue
While going through maze, she realized that current system of billing for medical services is somewhat opaque
As CEO
You may need to quickly find out company earnings information within 30 seconds
But obviously
Doctors don't know what billing is behind this
Deepika said
They don't know where money comes from
It is not clear what specific calculation and allocation factor is
Deepika
I see need again
and developed a new solution
Today
AthelasIn Remote Patient Monitoring and Revenue
Cycle control
revenue cycle management, called RCM
Innovations
helps
Countless private clinics and medical groups
Improved Continuous Billing
Deepika said
RCM will be backbone of Athelas business
Let
Opportunity to enter a field valued at over $100 billion
Sequoia partners think
The future of Athelas is not just health monitoring
Instead, extend preventive health insurance to everyone
Collaboration with Deepika and Tanai
Most Helpful
You will find that they are getting closer to their vision step by step
Also know how to keep expanding it
Represented by Deepika
Promoting change in healthcare industry
It's very easy to do - find people who really need help
And listen to them
Difficulty she didn't mention
Listening is not easy, but design is behind it
Organize group production and experimental testing
It all takes hard work
According to Deepika
Stick with your unique value proposition
—— Identify benefits
“Indistinguishable” similarities between stakeholders
These vacancies
Finally making Atelas
Development Leaps
Sensor and software infrastructure provider for modern healthcare industry
And her understanding
This is key to success
We have no shortage of people who want to innovate, be it doctors
The patient is still
Big and small companies throughout medical system
Deepika said
Talk to them and I'll ask what we can do
To makemake working with site easier and more convenient
They
This will clearly tell you what their needs are
Once you find a point where you can show your strength
This will open up endless possibilities
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